The influence of nutrigenetics on biomarkers of selenium nutritional status

Abstract Selenium (Se) is an essential micronutrient for human biology that executes its functions as the amino acid selenocysteine via selenoproteins, which have important in, example, antioxidation, immunomodulation, thyroid metabolism, and fertility. Se nutritional status assessed using quantification of blood biomarkers, are influenced by several factors, including diet, age, gender, smoking status, alcohol consumption, health condition, genetic characteristics individuals. Nutrigenetic studies identified single nucleotide polymorphisms in selenoproteins might clarify high variability values reported biomarkers different populations, response these to supplementation with either organic or inorganic forms Se. This review aims (1) define basic aspects biology, (2) describe current most commonly used (3) provide a summary associations between functional healthy populations.